Human AFMID AlphaFold model in 3D.
Q63HM1 · AF-Q63HM1-F1 · 303 residues · AlphaFold prediction
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Normal Liver shows the full-length model. Tumor Liver shows a conceptual Δexons5–9 overlay—not a solved tumor structure. These views illustrate isoform patterns, not every normal or tumor cell.
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Conceptual deletion overlay—not a predicted mutant fold or experimentally solved structure. The gray region maps to exons 5–9 in the wild-type model. A 472-nt skip shifts the reading frame; the remaining coordinates do not establish the mutant protein.
Outside exons 5–9Exons 5–9Catalytic residuesHGGYW motif
1–45678910–11
Exons 5–9 overlap residues 103–260; boundary codons are shared. One coral color marks exons 5–9 only—not AlphaMissense pathogenicity or AlphaFold confidence.
Model: AlphaFold DB v6 · UniProt Q63HM1 · Exons: ENST00000409257.10 (GRCh38) · Splicing study